Search results for "Sulfinic acid"

showing 4 items of 4 documents

Chemical and spectroscopical evidence for an electron‐transfer mechanism in the reaction of arenesulfonyl chlorides with anions

1989

The reaction of amide and amidate anions 2 with p-toluenesulfonyl chloride (1) under different reaction conditions gives rise to the total or partial reduction of the acyl halide to p-toluenesulfinic acid (5) and acylation compounds in variable amounts depending on the crowding at the anionic center. This indicates that a Single-Electron Transfer (SET) mechanism is involved in the reactions of 1 with anions. Unpaired electron species are detected by ESR in the course of the reactions.

chemistry.chemical_classificationInorganic chemistrySulfonyl halideSulfinic acidChlorideInorganic ChemistryAcylationchemistry.chemical_compoundElectron transferchemistryUnpaired electronAmidePolymer chemistrymedicineAcyl halidemedicine.drugChemische Berichte
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Antiasthmatic effects of onions: Inhibition of 5-lipoxygenase and cyclooxygenase in vitro by thiosulfinates and “Cepaenes”

1990

Nine thiosulfinates (TS) and four "Cepaenes" (CS) isolated from onions and/or synthetized by us showed dose dependent (0.25 to 100 microM) marked inhibitory effects on both cyclooxygenase (CA, tested on sheep seminal vesicle microsomes) and 5-lipoxygenase activity (LO, tested on porcine leukocytes). The following rank order of activity was observed: saturated aliphatic TS less than aromatic TS approximately alpha, beta-unsaturated TS less than CS. CS inhibited both CA and LO by more than 75% at 10 and 1 microM concentrations respectively. Most likely, these in vitro effects are responsible for antiinflammatory and antiasthmatic properties of onion extracts observed in vivo, at least in part.

MaleSwineClinical BiochemistryArachidonic AcidsPharmacologyAlliumStructure-Activity RelationshipLipoxygenasemedicineAnimalsCyclooxygenase InhibitorsDisulfidesLipoxygenase InhibitorsThiosulfinateArachidonic AcidSheepbiologyPlant ExtractsChemistryCell BiologySulfinic AcidsAsthmaIn vitroBiochemistryMechanism of actionEnzyme inhibitorArachidonate 5-lipoxygenasebiology.proteinMicrosomeCyclooxygenasemedicine.symptomProstaglandins, Leukotrienes and Essential Fatty Acids
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Phosphororganische Verbindungen, 65. Die selektive Abspaltung von Allylgruppen aus Allylphosphonium‐, ‐arsonium‐ und ‐sulfoniumsalzen und aus Allylsu…

1970

KCN spaltet Allylphosphonium-, -arsonium- und -sulfoniumsalze in Methacrylnitril und tertiare Phosphine, tertiare Arsine und Thioather auf. Durch alternierende Cyanolyse und Quartarisierung konnen Phosphonium- und Arsoniumsalze mit vier verschiedenen Liganden aufgebaut werden. Allylammoniumsalze, Allylphosphinoxide und -phosphonsaureester konnen nicht gespalten werden. Dagegen liefern Allylsulfone mit KCN in guten Ausbeuten Methacrylnitril und Sulfinsauren. Organic Phosphorus Compounds, 65. The Selective Elimination of Allyl Groups from Allylphosphonium, -arsonium and -sulfonium Salts and from Allyl sulfones by Cyanolysis KCN cleaves allylphosphonium, -arsonium, and -sulfonium salts to give…

Inorganic Chemistrychemistry.chemical_classificationchemistry.chemical_compoundArsinechemistryMethacrylonitrileSulfoniumOrganic chemistryOrganic phosphorusPhosphoniumSulfinic acidMedicinal chemistryPhosphineChemische Berichte
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STUDIEN ZUM VORGANG DER WASSERSTOFFÜBERTRAGUNG 621HERSTELLUNG UND ELEKTROREDUKTIVE SPALTUNG EINIGER ARYLDISULFONSÄUREDERIVATE

1982

Abstract Benzene-disulfonylchlorides were converted to the corresponding dialkyl-and diphenylesters, N-alkyl-and N-aryl disulfonamides. The half-wave-potentials E1/2 1 and E1/2 2 were measured and the products obtained on potentiostatic fission at E1/2 1 were isolated and characterized. The electroreduction of benzene-1,4-disulfonic acid-diphenylester in methanol yields phenol in a quantity approximately corresponding to the current passed, but no corresponding quantity of sulfinic acid. In dry acetonitrile, benzene-1,4-disulfonic acid diesters and diamides undergo potentiostatic fission (at E1/2 1) in good chemical and current yields, giving the corresponding monosulfonate-sulfinic acid or…

chemistry.chemical_classificationchemistry.chemical_compoundElectrical currentchemistryFissionPhenolOrganic chemistryAlcoholAmine gas treatingMethanolSulfinic acidAcetonitrileMedicinal chemistryPhosphorus and Sulfur and the Related Elements
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